Serum osteocalcin (OC) and alkaline phosphatase (ALP) were measured as markers of bone formation and fasting urinary calcium/creatinine (Ca/Cr) and a degradation product of type 1 collagen/Cr (Crosslaps TM ) (Type 1/Cr) as markers of bone resorption.

• 骨形成指标为血清骨钙素（OC）及碱性磷酸酶（ALP），骨吸收指标为空腹晨两小时尿I型胶原降解物/肌酐（Type1/Cr）和钙/肌酐（Ca/Cr）。