Safrole is synthesized from catechol through methylenation, selective bromination and Wurtz - Fittig reaction Respectively in yield 85.1%, 74.1%, 72.8% and in total yield 45.9%.

• 本文研究以邻苯二酚为起始原料；经亚甲基化、选择性溴化、武兹-菲提格反应三步合成黄樟油素；其三步收率分别为85.；1%25；74