STATs may convert and transmit downstream signal evoked by interaction between cytokines/ growth factors and their ligands.

• 转录因子STATs能将由细胞因子/生长因子及其受体相互作用激发的下游信号进行协调与转导，同样酪氨酸激酶JAKs也在信号转导途径中起着重要作用，二者调控着细胞的增殖与分化。