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- Rifamycine Chibret 力复霉素, 利福霉素[抗结核抗生素]
- AIM: To evaluate the clinical efficacy of rifamycin in the treament of community-acquired pulmonary infections. 目的:观察利福霉素对社区获得性肺部感染的疗效。
- Objective To observe the curative effect of rifamycin sodium injection on pulmonary tuberculosis patients. 目的观察利福霉素钠注射液(立复欣)治疗肺结核的临床效果。
- The reaction system and operation conditions for the oxidation of rifamycin B to rifamycin O were studied. 对利福霉素B氧化生成利福霉素O的反应体系和操作条件进行了实验研究。
- Uniform design method was employed to optimize the medium for production of rifamycin SV. 应用均匀设计的方法对利福霉素SV发酵培养基中的氮源配比进行优化。
- Arioli V, Berti M, Carniti G, et al. Antibacterial activity of DL473: a new semisynthetic rifamycin derivative. J Antibiotics, 1981,34:1026. 李拯民;王苏民.;耐药结核病的流行趋势
- Arioli V， Berti M， Carniti G， et al. Antibacterial activity of DL473， a new semisynthetic Rifamycin derivative. J Antikiotics, 1981，34: 1026. 何国钧，夏祥新，黄芝芳，等.;利福喷丁对初治肺结核的临床研究和三年随访报告
- Objective To optimize the content and feeding strategy of barbital sodium during the fermentation of rifamycin B in order to improve the yield. 目的优化利福霉素发酵摇瓶中巴比妥钠的添加量及添加策略,以提高发酵产量。
- In vitro assay showed that rifamycin was inhibitory to RNA polymerase from sporulating cells of wild-type strain,but not to that of the mutant. 此外，在营养生长期，野生型和突变体的RNA和蛋白质合成方式基本相同，但在孢子形成期，两者的合成在数量上有明显的区别。
- When it is applied in the fermentation test of rifamycin, the titer of rifamycin increases more than 15% compared with the old fermentation defoamer. 结果表明，利福黴素效价比原工艺提高15%25以上。
- Many natural products, such as Taxol, erythromycin and rifamycin have helped scientists to understand biological processes. 以往化学家对天然产物独有情钟,但仅仅以合成天然产物本身为最终目的。
- Methods 93 cases of pulmonary tuberculosis were treated by intravenous drip of rifamycin sodium injection(treatment group). 方法对93例肺结核采用静脉滴注利福霉素钠注射液治疗(治疗组)。
- METHODS The title compounds were designed and synthesized from rifamycin S, and the antibacterial activities of these compounds in vitro were tested. 方法以利福霉素S为原料合成目标化合物,并测定其抗菌活性。
- Objective:To study the relations between the polymorphic forms of rifamycin derivatives rifampicin(RFP), rifapentin(RFT) and rifamdeni(IPR) and the drug content in plasma(urine). 目的:探讨利福霉素类抗生素的衍生物(利福平,利福定,利福喷丁)的晶型与血(尿)药浓度的关系。
- In this paper,artificial neural network(ANN) was used to predict the relationship between the potency of rifamycin B and the fermentation medium minor error. 本文使用神经网络对历史数据进行处理,得到了利福霉素B培养基成份和发酵效价之间的关系;再以这个关系作为遗传算法的适应度函数,在一个相对大的空间内快速搜索最优解。
- As a derivative of rifamycin,rifalazil has a potential effect against Mycobacterium,which provides an alternative for curing the infections caused by multidrug-resistant Mycobacterium tuberculosis. 利福拉齐为利福霉素衍生物,有相当强的抗分枝杆菌活性,为目前多重耐药结核病的治疗提供了一种选择。
- Study on the Stability of Rifamycin Oxazine 利福霉素噁嗪稳定性的研究
- Keywords Rifamycin;Drug side effect;Liver toxicity; 关键词立复欣;药物副作用;肝毒性;
- Keywords rifamycin oxazine;rifampicin;stability; 利福霉素嗪;利福平;稳定性;
- Keywords rifamycin B;rifamycin O;oxidation; 利福霉素B;利福霉素O;氧化;
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