Results showed that crude drugs such as Ginseng Radix, Glycyrrhizae Radix and Zingiber Rhizoma had serious contamination, while using starch of lactose as excipients showed lesser degree of microbial contamination.

• 制程中造粒制程是重要的污染关键，与使用生药粉末或添加生药粉末作赋形剂、械普受污染及作业室落菌程度高有关。