Results The frequency of loss expression of DPC4 protein was 32.8% in BTCa, 47.3 % in CBD carcinoma ,11% in gallbladder carcinoma and 13% in HBD carcinoma.

• 结果DPC4蛋白的缺失表达率在胆总管癌中为47.；3%25；在胆囊癌中为11%25；在肝门部胆管癌中为13%25。