Results Mouse embryos were successfully hatched, adhered, implanted and outspreaded under the coculture system.The extraplacental cone and amniotic sac were formed as well.

• 结果小鼠胚胎在体外无血清培养体系中能够顺利孵化、粘附、种植及外延生长，并形成外胎盘锥和羊膜囊；