Result:The AGEs and PDGF-A concentrations were all significantly increased,the glomerular basement membrane grew wider,and the mesangium expanded.

• 结果：糖尿病大鼠肾小球终末糖化产物增加，肾小球血小板源生长因子-A明显增高，肾小球发生基膜增厚和系膜增宽的病理变化。