Response surface method was used to optimize the MRS-based enrichment medium of S. sativarius subsp thermophilus STX2. The influence of twelve additives and the initial pH of the media were evaluated using a Plackett-Burman design.

• 采用响应面方法对唾液链球菌嗜热亚种增殖培养基进行了优化。 以MRS培养基作为基础培养基,采用Plackett-Burman(PB)设计法,对12种乳酸菌生长促进因子以及培养基的初始pH等13个因素对唾液链球菌嗜热亚种STX2生长的影响进行评价。