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- Xeloda is contraindicated in patients with severe renal impairment. 希罗达禁用于严重肾功能不全患者。
- Objective To establish a hyperuricemic renal impairment model in rats. 目的建立大鼠高尿酸血症肾损害动物模型。
- This case suggests that vancomycin overdosage can produce reversible renal impairment in preterm neonates. 这例病人提示，过量的万古霉素可引起早产儿可逆性肾损害。
- Choose a drug of low cost, but exercise caution if hypoglycaemia may be a problem to the indiidual, including through renal impairment. 选择低价药物，但是要注意的是，如果个体有发生低血糖的危险（包括由于肾脏损害引起的），运动则要谨慎。
- Furthers study is needed of the role of low-osmolar contrast media in patients with severe renal impairment. 有关低渗性造影剂对于有严重肾功能损害病人的影响作用尚须进一步研究。
- Conclusion The moderate dose treatment is suitable for preparation of hyperuricemic renal impairment model in rats. 结论中剂量组作为高尿酸血症动物肾损害模型较为合适。
- Vancomycin overdosage can produce reversible renal impairment in preterm neonates. 过量的万古霉素可引起早产儿可逆性肾损害。
- Objective:To explore the influence of cytomegalovirus(CMV),herpes simplex virus(HSV) and coxsackie virus(COXV) infection on neonatal renal impairment. 目的 :研究新生儿巨细胞病毒 (CMV)、单纯疱疹病毒 (HSV)、柯萨奇病毒 (COXV )对肾脏影响。
- Choose a drug of low cost, but exercise caution if hypoglycaemia may be a problem to the individual, including through renal impairment. 选择低价药物，但是要注意的是，如果个体有发生低血糖的危险（包括由于肾脏损害引起的），运动则要谨慎。
- Elderly with severe renal impairment (Clcr <25 mL/minute) may have clearance reduced by >50% compared to healthy elderly subjects. 严重肾损伤的老年患者（Clcr<25mL/minute）其清除率与健康老年人相比，可能会下降50%25以上。
- Conclusion: Low-osmolar contrast media did not offer statistically significant benefits to patients with renal impairment. 结论：在肾功能损害的病人中，低渗性造影剂的使用并不能提供有统计意义的好处。
- Endothelin-1 contributes to increased systemic vascular resistance,vascular remoulding,left ventricular dysfunction and renal impairment in essential hypertension. 原发性高血压时血浆内皮素-1水平升高,可导致外周阻力增加,并且通过激活ETA和ETB受体可加重高血压病心、肾、动脉系统的损害,形成恶性循环。
- The potential benefits of the considerably more expansive nonionic media are likely to be quite small, at least in those with moderate preexisting renal impairment. 至少对于一些本身就有中度的肾功能损害的患者来说，更加昂贵的非离子型造影剂的潜在好处也可能非常少。
- Introduction: Use of radiographic contrast media can result in an acute toxic nephropathy, especially in patients with renal impairment caused by diabetic nephropathy. 介绍：使用放射造影剂可能引起急性肾毒性（急性中毒性肾病），特别是在由糖尿病肾病引起的肾功能损害的病人中。
- Where renal function tests are not routinely available for people on metformin, such tests are nevertheless required where the likelihood of renal impairment is high. 如果应用二甲双胍的人群肾功能检测不能形成常规，那么这样的检查在患者的肾功能损害形似升高时应当考虑应用。
- Begin with metformin unless eidence or risk of renal impairment, titrating the dose oer early weeks to minimize discontinuation due to gastro-intestinal intolerance. 如果没有肾脏受损或有受损危险的情况下，起始应用二甲双胍治疗。在最初的几周调整剂量，将由于胃肠道不适引起的停药减小到最少。
- Begin with metformin unless evidence or risk of renal impairment, titrating the dose over early weeks to minimize discontinuation due to gastro-intestinal intolerance. 如果没有肾脏受损或有受损危险的情况下，起始应用二甲双胍治疗。在最初的几周调整剂量，将由于胃肠道不适引起的停药减小到最少。
- Renal impairment: Use with caution in patients with renal impairment; clearance decreased significantly in severe impairment (Clcr <25 mL/minute) and dose reductions recommended. 肝损伤：肝损伤患者应避免使用或极度慎重使用；
- And there were also no significant risk for renal impairment on the use of energizing drinks after controlling age, gender, education level, income and body weight. 无论使用何种提神饮料，在控制年龄、性别、教育程度、收入、体重等五项变项后，对于肾功能不良皆无显著影响。
- One of the risk factors for late-onset renal impairment is the dose and level of the calcineurin inhibitor during the early months after transplantation. 迟发性肝脏损害的一个危险因子是在移植早期的几个月中神经钙蛋白抑制剂的剂量和水平。
