Remarkable immunogenicity of the TrxA/PEB1 fusion protein was well identified: A high titer of the specific antibody to CJ Pen19 whole antigen weredemonstrated, which could cross-reacted with purified TrxA/PEB1 fusion protein.

• （3）证实TrxA/PEB1融合蛋白有高度特异的免疫原活性： CJ Pen19全菌抗原免疫后4周在雄性新西兰兔诱发高滴度特异性抗体，可同时与Pen19菌体粗提蛋白和TrxA/PEB1蛋白发生特异性结合。