Recently studies in the knockout animals have discovered that ho-meobox (Hox) genes involve and regulate the skeleton morphogenesis, and the animal experiments also indicate Abd - B related HoxC genes expressing in the hindlimb.

• 近年来，在基因敲除的动物实验中发现Hox基因参与并调节骨骼形态发育，动物实验亦表明Abd-B组HoxC簇基因在下肢表达；