Recently it is suggested that glucocorticoid therapy might impair intestinal calcium absorption, dramatically suppress osteoblastic formation, and stimulate osteocyte apoptosis.

• 糖皮质激素性骨质疏松症的发病机制可能是其损害肠道的钙吸收,严重抑制成骨形成,刺激骨细胞的凋亡。