Recent work has uncovered that the acetylation of histones in chromatin are one of the key steps in the regulation of gene expression.

• 目前已经发现了组蛋白的乙酰化是细胞中调节基因转录的一种重要手段，组蛋白去乙酰酶的抑制剂可以改变基因的转录水平。