RESULTS:The cytotoxic activities of all these small compounds with planar ring were much less potent than those of the natural gambogic acid,and the introduction of prenyl to these small molec...

• 结果:这些具有平面环结构的小分子化合物的活性虽然比藤黄酸的活性要低,但是引入异戊烯基能显著提高其抗肿瘤活性。结论:藤黄酸结构中的异戊烯基和桥环结构对其抗肿瘤活性有着很重要的作用。