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- BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor. 背景与目的:全长型脾脏酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到细胞核内,作为转录抑制因子调节基因的转录。
- Relationship between the spleen tyrosine kinase and biological character of keloid fibroblasts 脾酪氨酸激酶与瘢痕疙瘩成纤维细胞生物学性状改变的关系
- Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer 脾酪氨酸激酶基因的再激活对胃癌生成和发展的影响
- spleen tyrosine kinase 脾酪氨酸激酶
- Spleen tyrosine kinase (Syk) 脾酪氨酸激酶
- The name is soluble f-m-s-like tyrosine kinase one? 这种蛋白质叫做可溶解fms样酪氨酸激酶一，
- OBJECTIVE:To discuss the progress and the clinical application evaluation of protein tyrosine kinase(PTK) inhibitors. 目的:探讨酪氨酸激酶抑制剂的进展与临床应用评价。
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase (PTK). 摘要目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase(PTK). 目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer? PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?
- Receptor tyrosine kinase (RTK), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity, has many members and complicated signal transduction pathways. 摘要受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族，成员众多，信号转导通路复杂多样。
- The inhibitor of VEGF receptor tyrosine kinase was introduced in detail. 详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
- Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor. 苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
- The ABL gene encodes a tyrosine kinase whose activity is tightly regulated. ABL基因编码一种活性受到严格调控的酪氨酸激酶。
- DDR2 is a newly identified receptor protein tyrosine kinase, which is composed of three parts: DR region on the N terminus, a long justatransmembrane region (JM) between DR region and transmembrane region, and intracellular region in cytoplasma. DDR2是一类新发现的受体型蛋白酪氨酸激酶，其分子结构由三部分组成：一是N端的DR区，二是在DR与跨膜区之间的很长的邻跨膜区(justatransmembrane region，JM)，三是在胞浆内的胞内区。
- AIM:To evaluate the relationship between spleen tyrosine k in ase(Syk)and the biological charcter of keloid fi broblasts(KFB)based on the research of signal transduction of keloid fibro blasts. 目的:通过瘢痕疙瘩成纤维细胞(KeloidFibroblasts,KFB)信号传递的研究,探讨脾酪氨酸激酶(SpleenTyrosineKinase,Syk)与KFB生物学性状改变的关系。
- ABSTRACT STI571 is one of the target drugs to Bcr/Abl oncoprotein.It is a special inhibitor to the activation of protein tyrosine kinase by interrupting phosphorylation of substrate. 摘 要 STI571 是一种针对Bcr/Abl基因表达产物的靶向治疗药物，可以阻止底物的酪氨酸残基磷酸化，发挥特异性酪氨酸蛋白激酶活性抑制作用，临床研究结果证明对慢性粒细胞白血病的疗效显著优于干扰素及其它化疗药物。
- FGFR3, a member of polypeptide growth factor family, is a tyrosine kinase receptor. FGFR3是这一多肽类生长因子的家族成员之一，它是一种酪氨酸激酶受体。
- The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models. 本文综述了近年来酪氨酸激酶抑制剂的研究进展，包括抑制剂的结构和与激酶作用的药效团模型。
- Isoflavone. Inhibitor of EGFR tyrosine kinase, blocking phosphatidylinositol turnover. 异黄酮类。抑制EGFR酪氨酸激酶。阻断磷脂酰肌糖的翻转。
