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- Could RNA interfere with prion disease? RNA能否干预普粒子疾病？
- We have shown an initial proof of this principle by following the evolution of prion disease in mice. 我们藉由追踪实验小鼠体内普恩蛋白疾病的进展，对这个理论有了初步的验证。
- This paper reviews the basic feature,chemical structure of prion protein and prion disease,plausible physical functions of PrPc. 介绍了朊病毒的基本特征、化学结构以及可能具有的生理功能:参与神经系统功能的维持;
- Prion diseases can be controlled, if not eradicated. 如果说普朊病难以彻底消除的话,那也是可以控制的。
- Quinacrine has been administered orally to patients with vCJD and to individuals who have the sporadic or genetic forms of prion disease. 奎纳克林曾以口服方式开给vCJD患者，以及患有偶发性或遗传性普恩蛋白疾病的人们。
- Prion diseases affect the brains of a number of mammals, including humans. 普利子疾病能影响许多哺乳动物的大脑，包括人类。
- There is currently no treatment for prion diseases, which include CJD in humans and boine spongiform encephalopathy (BSE) in cattle. 目前还没有普粒子疾病的治疗办法，包括人类的克雅氏病（CJD）和牛脑海绵状病（疯牛病，BSE）。
- The incubation period of prion diseases may span upward of40 years, and CWD has been spreading noticeably in only the past10. 普恩蛋白病变的潜伏期可能长达40年，而慢性消耗病的散播受到注目，还只是过去10年的事。
- Investigators are also hopeful that when a successful therapy for prion disease is developed, it will suggest effective therapies for more common neurodegenerative diseases, including Alzheimer's, Parkinson's and amyotrophic lateral sclerosis( ALS). 研究人员也怀抱著希望，如果能够发展出有效治疗普恩疾病的方法，将可提供线索来有效治疗其他更常见的神经退化疾病，包括阿兹海默症、金森氏症以及侧索硬化肌萎缩症等。
- The incubation period of prion diseases may span upward of 40 years, and CWD has been spreading noticeably in only the past 10. 普恩蛋白病变的潜伏期可能长达40年，而慢性消耗病的散播受到注目，还只是过去10年的事。
- Now the scientists want to move on and look for alternative sample-taking methods for diagnosing and tracking prion diseases in humans in early stages. 现在，科学家们想继续前进，并寻找其他采样方法，以供诊断和跟踪朊病毒疾病在人类尚处于初期阶段。
- The rarity of prion diseases and the low national consumption of deer and elk (compared with beef) make it hard to draw any firm conclusions. 由于普恩蛋白疾病十分稀少，相对于牛肉，美国对鹿与麋鹿的消费量也较低，因此很难下明确的结论。
- Prion diseases are always fatal, often, however, not until months after the outbreak of the disease.As yet there is no cure. 朊病毒病是致命的，常常在发病后数月死亡，但是目前还没有有效的治疗方法。
- Prion diseases are always fatal, often, howeer, not until months after the outbreak of the disease.As yet there is no cure. 朊病毒病是致命的，常常在发病后数月死亡，但是目前还没有有效的治疗方法。
- His disease was complicated by pneumonia. 他的病因肺炎并发症而变得更严重。
- Still, scientists say new forms of prion diseases have arisen lately, and there's concern that they could hop to humans. 尽管如此，科学家说近来出现了一些新的朊病毒疾病，人们担心这些疾病可能会传播到人类身上。
- Cytokines related to Prion disease 朊蛋白病相关的细胞因子
- Prion diseases is a kind of infectious,sporadic or genetic neurodegenerative disorders in both humans and animals,including scrapie in sheep,BSE in cattle and CJD in humans. 朊病毒疾病是人和动物中的一种传染性、散发性和遗传性的神经退行性脑病。
- We should transform the traditional medical thinking model to research the mystery of prion.The appearances of prion diseases are discussed from philosophical angle. 必须转变固有的医学思维模式来看待朊病毒之谜,并从哲学角度探讨了朊病毒病的出现。
- In this course, the molecular and biochemical basis of the prion diseases, which include bovine spongiform encephalopathy (mad cow disease), Creutzfedt-Jakob disease and kuru will be examined. 在本课程中，我们将分析包括了牛海绵体样脑病（疯牛病），克雅氏症，以及库鲁病的朊蛋白疾病的分子和生化的成病基础。
