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- Aldose reductase is a key regulatory enzyme in the substrate flux via polyol pathway. 醛糖还原酶是糖代谢多元醇通路的限速酶。
- Epalrestat is the only available and specific inhibitor of aldose reductase.It can exert its action by blocking polyol pathway. 摘要依帕司他是目前唯一上市的醛糖还原酶特异性抑制剂，通过阻断多元醇通路而发挥作用。
- The polyol pathway increases the retinal ratio of the reduced form of nicotinamide adenine dinucleotide(NADH) and the oxidized form of nicotinamide adenine dinucleotide(NAD +) causing retinal hypoxia like redox imbalance,or "pseudohypoxia". 多原醇途径使视网膜内还原型烟酰胺腺嘌呤二核苷酸(NADH)和氧化型烟酰胺腺嘌呤二核苷酸(NAD+)比率升高,模拟低氧反应,改变了视网膜内氧化还原平衡。
- Keywords aldose reductase;diabetic keratopathy;polyol pathway; 醛糖还原酶;糖尿病性角膜病变;多元醇通路;
- Activation of Polyol Pathway and Its Mechanisms Induced by Glucose in Human Vascular Endothelial Cells 葡萄糖对人血管内皮细胞多元醇通路的激活作用及其机理
- The Effect of Jinmaitong Composita on the Polyol Pathway of Glucose Metabolism in Len of Diabetic Rat 筋脉通对糖尿病大鼠晶体多元醇代谢的影响
- Effects of Tang-zhang-ming on Polyol Pathway in Crystalline Lens of Diabetic Rats 糖障明对糖尿病大鼠晶状体多元醇通路的影响
- STUDY ON THE POLYOL PATHWAY AND Na-K-ATPase ACTIVITY IN KIDNEY OF ALLOXAN-INDUCED DIABETIC RATS 糖尿病大鼠肾脏多元醇通路和Na-K-ATP酶活性的研究
- Keywords Nitric oxide;Peritoneal mesothelial cells;Aldose reductase;Polyol Pathway;Peritoneal dialysis; 一氧化氮;腹膜间皮细胞;醛糖还原酶;多元醇通路;腹膜透析;
- Keywords Aminoguanidine;Peritoneal mesothelial cells;Aldose reductase;Polyol pathway; 氨基胍;腹膜间皮细胞;醛糖还原酶;多元醇通路;
- Keywords aloe medicated serum;glomerular mesangial cell;oxidative stress;polyol pathway; 芦荟药物血清;肾系膜细胞;氧化应激;多元醇通路;
- Keywords Glucose;Endothelium;Vascular;Polyol Pathway;Aldehyde Reductase;Nitric Oxide; 葡萄糖;内皮;血管;多元醇通路;醛糖还原酶;一氧化氮;
- Keywords Polyol Pathway;Aldose reductase;Peritoneal mesothelial cells;Peritoneal dialysis;Nitric oxide;Aminoguanidine; 关键词腹膜透析;腹膜间皮细胞;醛糖还原酶;多元醇通路;一氧化氮;氨基胍;
- They walked along the pathway toward the house. 他们沿著小路向那所房子走去。
- The pathway was rough and covered with little stones. 这条路高低不平，铺满了小石头。
- Polyol Pathway 多元醇通路
- Evaporation is a significant environmental pathway. 蒸发作用是一个重要的环境途径。
- The pathway across the field was covered by snow. 穿过田野的小径被雪覆盖了。
- Linking two neurons in a neuronal pathway. 连接性的在神经细胞路径上连接两个神经原的
- They are in the pathway of everyone. 这些难题就横亘在每一个人的人生道路上。
