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- Peptide nucleic acids(PNA) are DNA mimics that bind strongly to DNA and RNA in a sequence specific manner. 肽核酸(PNA)是DNA模拟物,能与DNA和RNA以序列特异性方式结合,在基因研究和基因治疗方面有广泛的应用前景。
- Peptide nucleic acids (PNA) are DNA mimics that bind strongly to DNA and RNA in a sequence specific manner. 肽核酸(PNA)是DNA模拟物,能与DNA和RNA以序列特异性方式结合,在基因研究和基因治疗方面有广泛的应用前景。
- Objective To investigate the effects of ion concentrations of PBS buffer on hybridization efficiency with peptide nucleic acid(PNA) leaky surface acoustic wave(LSAW) gene sensor. 目的探讨PBS缓冲液的离子浓度对构建的肽核酸(PNA)漏声表面波(LSAW)基因传感器杂交效应的影响。
- People has developed some kinds of mimics of oligonucleotides , among them there is Peptide Nucleic Acid(PNA), which was first synthesized by scientists at the University of Copenhagen(Nielsen, Egholm et al). 肽核酸是一种寡核苷酸的类似物 ,它是由丹麦哥本哈根大学的Nielsen、Egholm等人首先发明合成的。
- Peptide nucleic acid(PNA) is a nucleic acid analog in which the sugar phosphate backbone of natural nucleic acid has been replaced by a synthetic peptide,resulting in an achiral and uncharged mimic. 肽核酸是一核酸类似物,是核酸中的糖-磷酸主链被一合成的肽链所取代,最终形成一种非手性的、不带电荷的类似物。
- Current Situation of Peptide Nucleic Acid Research 肽核酸的研究现状
- Progresses in antisense peptide nucleic acid and it's application 反义肽核酸的研究进展及应用
- Keywords peptide nucleic acids (PNA);macrocyclic polyamine;synthesis;uracil; 肽核酸;大环多胺;合成;尿嘧啶;
- Keywords peptide nucleic acid;antisense;dendritic cells;receptor;chemokine; 肽核酸;反义;树突细胞;受体;趋化因子;
- Keywords peptide nucleic acid;PNA monomer;serine;histidine;synthesis; 肽核酸;肽核酸单体;丝氨酸;组氨酸;合成;
- Design and Synthesis of New Chiral Peptide Nucleic Acids Containing Hydroxyl and Imidazole Groups 含羟基和咪唑基团新手性肽核酸的设计与合成
- Synthesis and Characterization of Peptide Nucleic Acid Monomeric Backbone Bonded Porphyrins 肽核酸骨架分子键联卟啉的合成及结构表征
- Synthesis of Chiral Peptide Nucleic Acid Monomers Containing Serine and Histidine Residues 含丝氨酸和组氨酸残基手性肽核酸单体的合成
- Blocking the CC chemokine receptor 5 pathway by antisense peptide nucleic acid prolongs islet allograft survival 反义肽核酸阻断CC趋化因子受体5途径延长同种异体胰岛移植物存活
- Research of new style biological signal amplification system of peptide nucleic acid piezoelectric gene sensor 肽核酸压电基因传感器新型生物信号放大系统的研究
- The Effects of Anti-sense Peptide Nucleic Acids Targeting Ki-67 mRNA on Implanted Human Renal Cell Carcinoma in Nude Mice 反义Ki-67肽核酸对裸鼠人肾癌细胞移植瘤的治疗作用
- Keywords Yersinia pestis;peptide nucleic acid;magnetic beads;fluorescence scan technology; 鼠疫耶尔森氏菌;肽核酸;磁珠;荧光扫描技术;
- Is a infectious protein without nucleic acid. 无核酸的传染性蛋白。
- DNA and RNA are both types of nucleic acid. 脱氧核糖核酸和核糖核酸是两种类型的核酸。
- Keywords triple-helical DNA;peptide nucleic acid;antisense technology;antigene technology;gene strategy; 关键词三链DNA;肽核酸;反义技术;反基因技术;基因治疗;