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- K ras gene point mutation at codon 12 was found in human pancreatic carcinoma cell line PC 2, and the mutation style was CGT. 人胰腺癌细胞株PC 2存在K ras基因点突变 ,突变方式为CGT。
- Abstract:Objective To observe the effect of photodynamic therapy(PDT)on human pancreatic carcinoma cell lines in vitro. 摘 要:目的 探讨光动力作用(PDT)对体外培养的人胰腺癌细胞的杀伤效应。
- Methods Human pancreatic carcinoma cell lines SW1990, Capan-1 (Cap), AspC-1 (ASPC), P3, PANC-1 (Pan-1) and MIAPaCa-2 (MIA) were tested for MT level and radio-sensitivity using ELISA and clonogenic assay, respectively. 方法分别采用外源性锌离子及反义寡聚核酸(AS)转染P3、Pan-1、MIA、SW1990、Cap、ASPC等6株胰腺癌细胞,调节MT表达,随后应用ELISA及集落实验检测MT表达水平及放射敏感性指标存活分数(SF2)的变化。
- The MTT assay and median-effect principle were used to observe theinteraction of 5-fluorouracil ,cisplatin and epirubicin on human pancreatic carcinoma cell line Aspc-1.Results: l. 采用MTT测定5一FU、DDP和E一ADM单用及两两合用时对细胞株AsPc 一1的抑制作用,并应用中效原理判定药物合用的效果。
- To study the inhibition effect of E. coli cytosine diaminase (CD)/5-flurocytosine (5-FC) system on the growth of human pancreatic carcinoma cell line cells. 目的探讨大肠杆菌胞嘧啶脱氨基酶(CD)/5-氟胞嘧啶(5-FC)系统对人胰腺癌细胞的体内外生长抑制作用。
- Results: Adeno-X-SSTR2,recombinant adenovirus vector,can infect pancreatic carcinoma cells MIA-PaCa-2 and AsPC-1 efficiently,which both can express SSTR2 mRNA and their protein. 在不同浓度NC-8-12和奥曲肽作用下;未转染SSTR2基因胰腺癌细胞株的Survivin表达量无明显变化(P>0.;05);转染了SSTR2基因胰腺癌细胞株的Survivin表达量明显下调(P<0
- The expression of K-RAS P21 protein in AsPC-1 and MiaPaCa-2 pancreatic carcinoma cells was obviously lower after the transduction of specific K-RAS Antisense gene,which has little impact on BxPC-3 pancreatic carcinoma cells. 转导K-RAS突变特异性反义基因后,AsPC-1和MiaPaCa-2胰腺癌细胞的K-RAS P21蛋白表达明显降低; BxPC-3胰腺癌细胞的K-RAS P21蛋白表达无明显变化。
- Keywords Prodigiosin;human pancreatic carcinoma cell;prolif eration inhibitor; 灵菌红素;胰腺癌肿瘤细胞;增殖抑制;
- Effects of somatotropin on telomerase activity in human pancreatic carcinoma cell line 生长激素对胰腺癌细胞株端粒酶活性的影响
- Keywords adenovirus;neurite growth-promoting factor;PTN;short hairpin RNA(shRNA);pancreatic carcinoma cell; 重组腺病毒;神经轴突过度生长因子;PTN;短发夹RNA;胰腺癌细胞;
- Interaction between 5-fluorouracil,mitomycin and epirubicin on human pancreatic carcinoma cell line Aspc-1 and Bxpc-3 5-氟尿嘧啶、表阿霉素、丝裂霉素单用及合用时对胰腺癌细胞Aspc-1和Bxpc-3的抑制作用
- Extended resection for pancreatic carcinoma. 胰腺癌的扩大切除术。
- Inhibition of target gene expression of human pancreatic carcinoma cell by antisense oligonucleotide specific to K-ras point mutation K-ras基因点突变的反义寡脱氧核苷酸对人胰腺癌靶基因表达的抑制作用
- The study of the effect of antisense oligonucleotide specific to K-ras point mutation on human pancreatic carcinoma cell PC-2 针对于K-ras基因点突变的反义寡脱氧核苷酸对人胰腺癌细胞株PC-2作用的研究
- Antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene transfection mediated by adenovirus in human pancreatic carcinoma cell 肿瘤坏死因子相关凋亡诱导配体的抗胰腺癌细胞的作用
- The effect and possible mechanism of human recombinant growth hormone on proliferation of bile duct carcinoma and pancreatic carcinoma cell lines in vitro 生长激素在体外对胆、胰细胞株的增殖及其可能机制的实验研究
- Expression and significance of SMO mRNA in pancreatic carcinoma. 胰腺癌组织中SMO mRNA的表达及其临床意义
- Photodynamic Effects of CPD_5 on Human Pancreatic Carcinoma Cell Lines in Vitro and Reduced Poisonous Reaction Under Photosencitivity by Using Vitamin C CPD_5的光动力作用及维生素C抗光毒效果
- Growth modulation of stilamin on human pancreas carcinoma cell line ASPC-1 思他宁对人胰腺癌细胞株ASPC-1的生长调控
- In the center is a duct lined by carcinoma cells. 中央为有癌细胞排列于其中的导管。