PF4 belongs to the subgroup of non-ELR CXC chemokines. Chemokines with ELR can stimulate newborn blood vessel development, but PF4 has no such effect.

• PF4属于CXC趋化因子非ELR基序的亚型,具有ELR基序的有血管新生刺激活性,而PF4无此基序,故没有促进血管新生的作用,反而抑制血管的生成。