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- Keywords PEGylated trichosanthin;abortifacient activity;systemic anaphylaxis reaction;passive cutaneous anaphylaxis; 聚乙二醇化天花粉蛋白;抗生育活性;全身过敏反应;被动皮肤过敏反应;
- PEGylated trichosanthin 聚乙二醇化天花粉蛋白
- Usually in China it is used in combination with pegylated interferon. 有时,患者有利巴韦林耐受的问题。
- Similar situation is also present in the homologous protein trichosanthin. 类似的情况在同源蛋白天花粉蛋白中也是存在的。
- Objective :To investigate general alleigical reaction effect of trichosanthin(TCS) injection on guinea pig . 目的:观察天花粉蛋白(TCS)注射液致豚鼠全身过敏反应的情况。
- Based on that study, I think it is right to think about combinations of pegylated interferon and tenofovir. 这类研究应该能得到研究者和权威教育机构的鼓励。
- GUS and TCS (trichosanthin) genes were introduced into wheat via the pollen-tube pathway. 切除羽状柱头后,在小麦花柱切面上滴注含有GUS与天花粉蛋白基因的质粒DNA。
- Pro.McCaughan: I'm a bit of a nealist about the two forms of pegylated interferon. McCaughan教授:对这两种干扰素的看法,我比较倾向于现实主义。
- H?2 Ag was conjugated with trichosanthin (TCS) by heterobifunctional reagents SPDP and 2?IT. 异型双功能试剂(SPDP,2-IT)连接H-2Ag和天花粉蛋白(TCS);
- To study the inhibitory effect of purified trichosanthin component on the proliferation of malignant melanoma. 目的:探讨中药天花粉蛋白纯化组分对恶性黑色素瘤细胞增殖的抑制作用。
- Trichosanthin (TCS) is a kind of anti-tumor medicine, showing great cytotoxicity to cells (JAR). 天花粉蛋白是一种抗肿瘤药物,对绒毛膜上皮癌细胞的杀伤力特别强。
- Objective: To study the effect of trichosanthin on proliferation of lung carcinoma cell line A549 cells in vitro. 目的:观察天花粉蛋白对人肺腺癌细胞株A549生长增殖的影响。
- In summary, we PEGylated the N-terminus of rhG-CSF in a site-specific manner with mPEG-PAL through a reactive terminal aldehyde group. 创新训练计划,增强了我们的团队合作意识。无论是在实验过程中,还是在项目申请和文献查阅上,团队合作精神都得到了很好的锻炼;
- ABSTRACT Objective :To investigate general alleigical reaction effect of trichosanthin(TCS) injection on guinea pig. 摘要 目的 :观察天花粉蛋白(TCS)注射液致豚鼠全身过敏反应的情况。
- In the interim prior to licensure of these new small molecule inhibitors, established therapy with pegylated interferon and ribavirin can be tailored. 在这些新型小分子抑制剂获得临床使用许可前,我们可以对业已形成的聚乙二醇化干扰素联合病毒唑的治疗方案进行适当的修改。
- The potential of the PEGylated PAMAM dendrimer as an anti-tumor drug carrier was evaluated using methotrexate(MTX) as a model drug. 通过包裹与释放实验研究该药物载体对抗癌药物甲氨蝶呤(MTX)的包裹及释放能力。
- In addition, the morphological changes and damaging effect of trichosanthin (TCS) on red blood cell (RBC) membrane were observed by AFM. 天花粉蛋白(TCS)和红细胞的相互作用,利用AFM观察到天花粉蛋白(TCS)和红细胞相互作用前后红细胞膜超微结构的变化,据此讨论了二者的作用机理。
- Trichosanthin is a singlechain ribosome inactivating protein with effective anti-tumor action extracted from the root of T.Kirilowii Maxim. 天花粉蛋白是从葫芦科植物栝楼块根中分离纯化得到的单链核糖体失活蛋白,药理学研究发现其具有较强的抗肿瘤作用。
- Individualizing dose and duration of pegylated interferon and ribavirin according to on-treatment virologic response may improve sustained virologic response rates. 据治疗过程中的病毒反应,聚乙二醇干扰素和利巴韦林的个性化剂量和疗程,能有效改进耐药反应。
- Abstract Objective: To investigate the co-inhibition effect of trichosanthin (TCS) and arsenacetylic acid( ASAC )on hepatoma cells of SMMC-7721. 摘 要 目的:了解天花粉蛋白(TCS)与胂酸基乙酸(ASAC)对SMMC-7721细胞生长的协同抑制效果。