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- The protein binding selectivity of clozapine was discussed. 讨论了氯氮平蛋白结合作用的选择性。
- OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride. 目的:测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。
- Competitive protein binding assay indicates the level of cAMP is improved when CDCA is given by oral administration. 通过竞争性蛋白质结合分析法测得,鹅去氧胆酸经灌胃给药后能显著提高大白鼠气管组织中cAMP的含量。
- Method H?3?cAMP was used in protein binding assay to determine the level of cAMP in bovine BTC. 方法运用蛋白竞争结合法用氚(H3)标记的环磷酸腺苷(adenosine3,5?cyclicmonphos?phate,cAMP)测定牛眼小梁细胞内cAMP的含量。
- Methods: Activity of PKC was determined by using competitive protein binding method. 方法:应用竞争蛋白结合法检测PKC活性。
- Drug protein binding changes involved in numerous factors in vivo may cause changes of pharmacokinetic parameters. 体内各种因素引起的药物与血浆蛋白结合的改变,可能导致相应的药代动力学参数变化。
- Hypocalcaemia (low calcium) is also seen due to poor absorption of vitamin D and calcium, and secondary to low protein binding of calcium. 低血钙有时也会发生,因为维生素D和钙质的吸收不良和低蛋白结合钙。
- A major role: Botox is the world's recognized best wrinkle agent, a protein binding Biochemical Technology, safe and effective, no side effects. 主要作用:肉毒杆菌素是当今世界公认的最佳除皱剂,属蛋白结合生化科技,安全有效,绝无副作用。
- The content and speciation analysis of protein binding speciation of trace elements Fe,Zn,Cu,Mn in the pollens of rape,maize,tea and lotus were studied by AAS. 以油菜、玉米、茶及莲花粉为实验材料 ,应用原子吸收分光光度法测定了 4种花粉中微量元素 Fe、Zn、Cu、Mn的蛋白质结合态含量及形态分布。
- Because the problems associated with protein binding are more prevalent in lateral-flow assays, this article will focus especially on issues relating to such systems. 因为在侧向流动试剂中,关于蛋白固定的问题很普遍,所以这篇文章主要集中这些系统相关的问题。
- The likelihood of interactions is low due to limited metabolism and plasma protein binding and almost complete renal elimination of unchanged lamivudine. 由于有限的代谢和血浆蛋白结合,相互作用的可能性很低,因为不变拉米夫定几乎完成肾脏消除。
- Results: The serum NPSH decreases markedly in children with diarrhea and pneumonia, the total sulfhydryl and protein bind sulfhydryl do not change obviously. 结果:表明肺炎及腹泻患儿血清NPSH明显降低,总巯基和蛋白结合巯基无明显改变。
- After renaturation, AIF protein binded DNA and induced nuclear apoptosis. 经EMSA与Hoechst 33258染色实验证实:获得的AIF蛋白具有良好地与DNA结合并可诱导肿瘤细胞核凋亡的能力,凋亡率为37%25。
- The pharmacokinetic profile of Lev closely approximates the ideal characteristics expected of an antiepileptic drug, with good bioavailability, linear and time-invariant kinetics, minimal protein binding, and least metabolism. 左乙拉西坦几乎具备了较好的抗癫痫药物的所有药动学特性:生物利用度高、线性曲线、低蛋白结合率、无肝酶诱导作用。
- After the preparation of this compound, the kinetics of blood clearance in rabbits, biodistribution in mice, measurement of plasma protein binding rate, and myocardial perfusion imaging in dog were carried out. 其内容包括 :99m Tc- Q3在兔体内的血药清除动力学、血浆蛋白结合率、小鼠体内分布、家犬显像及异常毒性试验等。
- Alkaline phosphatase(ALP),osteocalcin or bone Gla-containing protein(BGP)and cyclic adenosine monophosphate (cAMP)levels were measured by chemical method,radioimmunoassay and competitive protein binding method,respectively. 采用“金氏”化学法、放射免疫法和竞争蛋白结合法测定碱性磷酸酶(ALP)、骨钙素(BGP)和环磷酸腺苷(cAMP)浓度;
- OBJECTIVE:In this paper, the principle, feature and its application to the protein binding study of chiral drugs by High performance capillary electrophoresis /frontal analysis (HPCE/FA) are reviewed. 目的:综述了高效毛细管电泳/前沿分析(HPCE/FA)方法的原理、特点、及其在手性药物-蛋白结合研究中的应用。
- Protein Binding The plasma protein binding of tranexamic acid is about 3% at therapeutic plasma levels and seems to be fully accounted for by its binding to plasminogen (does not bind serum albumin). 治疗水平的氨甲环酸蛋白结合率大概在3%25左右,应该大多数都是与纤溶酶原蛋白相结合的。
- The studies revealed that the resistance formation of rice stem borer was closely involved with the increase of detoxifying enzyme activity,target enzyme insensitivity and protein binding. 已有研究表明:解毒酶活性升高、靶标不敏感性以及蛋白质的螯合作用与二化螟抗药性形成的关系密切。
- DNA helix can have subtle structural variations in its grooves and its physical arrangement that affect how well proteins bind to it. 在其凹槽和物理排列方面,DNA螺旋可以有微妙的结构变化,从而可以影响蛋白与之结合的程度。