Our results suggest that MBP and PLP might play some important role in initiating demyelinating diseases, and that M87-106, P40-60, P95-117 and P185-206 might be candidates for antigen epitope relevant to MS.

• 作为神经髓鞘主要成分的 MBP和 PLP免疫反应性高 ,可能在体内触发自身免疫反应过程发挥作用 ,而 M87-1 0 6、P40 -60、P95 -1 1 7和 P1 85 -2 0 6等位点值得进一步研究。