Oral administration of 20 to 40 mg/kg of matrine can protect gastric mucosa injury of rat caused bystress,hydrocbloric asid,alcohol, indomethacin and pyloric ligation.

• 预先口服20、40mg/kg苦参碱能够显著抑制大鼠应激、盐酸、乙醇、消炎痛所致的胃粘膜损伤。 40mg/kg苦参碱对不同方法所致胃粘膜损伤抑制率分别为32.；7%25、48