Once-daily sulfonylureas should be an available option where drug concordance is problematic. Rapid-acting insulin secretagogues may be useful as an alternative to sulfonylureas in some insulin-sensitive people with? exible lifestyles.

• 如果有药物依从性的问题时，一日一次的磺脲类药物是个比较合适的选择。在那些生活方式比较灵活的胰岛素敏感个体中，应用速效胰岛素促泌剂来代替磺脲类药物会比较有用。