Objective:To investigate the effects of lymphocyte proliferation using the synthetic oligodeoxynucleotide containing CpG motif(CpG ODN) as immunal adjuvant immunized with the recombinant hepatitis B surface antigen(rHBsAg) in mice.

• 目的:进一步探讨以合成含CpG基序的寡核苷酸(CpG ODN)作为免疫增强剂与重组乙型肝炎表面抗原(rHB-sAg)联合免疫小鼠,观察其淋巴细胞增殖反应效应。