Objective: To prepare paclitaxel-loaded poly(lactic-co-glycolic acid) microspheres containing isopropyl myristate (IPM) , and evaluate the release efficacy of the microspheres in vitro/in vivo.

• 目的:制备包含肉豆蔻酸异丙酯(IPM)的紫杉醇长效缓释微球,并对制备工艺及体内外缓释效果进行评价。方法:使用改良的单乳溶剂蒸发法制备紫杉醇长效缓释微球。