Objective To study the variable number tandem repeats(VNTR)polymorphism in intron 4 of the endothelial nitric oxide synthase(eNos)gene and its relationship with plasma NO in patents with PAH of COPD.

• 目的探讨内皮型一氧化氮合酶(endothelial nitricoxide syehtase,eNos)基因第4内含子27bp可变数目的短片段重复序列(variable number tandem repeats,VNTR)的多态性现象与慢性阻塞性肺部疾病(COPD)肺动脉高压的相关性。