Objective To study the effects of actinomycin D(ACTD) and VM-26 on proliferation in rat glioma cells C6.Methods The inhibition effect of actinomycin D or VM-26 was compared in treatment of rat glioma cell line by 3H-TdR method in vitro.

• 目的研究放线菌素D(Actinomycin D,ACTD)和替尼泊甙(Teniposide,VM-26)对大鼠胶质瘤细胞增殖的影响。 方法应用免疫细胞化学方法,观察C6细胞经不同剂量ACTD和VM-26作用48h后PCNA、CyclinD1表达的改变,FCM法分析细胞凋亡;