Objective To reproduce a rat model of disseminated intravascular coagulation (DIC) accompanied by multiple organ dysfunction syndrome (MODS) induced by endotoxin.

• 目的建立一种感染性弥散性血管内凝血(DIC)伴多器官功能障碍综合征(MODS)大鼠模型。 方法健康清洁级Wistar大鼠24只,随机分为正常对照组、低剂量脂多糖(LPS)组、中剂量LPS组和高剂量LPS组,每组6只。