Objective To prepare solid lipid nanoparticles(SLN) loaded with silibinin(SIL) extracted from traditional Chinese medicine and study the anti-fibrotic effects in model rats of liver cirrhosis.

• 目的制备载中药水飞蓟宾(SIL)的固体脂质纳米粒(SLN),并观察其对肝硬化模型大鼠的抗肝纤维化作用。