Objective To investigate the impacts of cytotoxic drugs on APE/ref-1 expression in A549 cell, in order to find the potential relationship between APE/ref-1 and chemoresistance of NSCLC.

• 目的 研究细胞毒性药物对A549细胞APE/ref-1表达的影响,初步探讨APE/ref-1与NSCLC耐药性产生的相关性。