Objective To investigate the expression level of cyclinD2and CDK4protein in breast carcino- ma, and their relationship to p27kip1protein and clinicopathological factors as well as the prognostic fac- tors in breast carcinoma.

• 目的研究乳腺癌组织中细胞周期蛋白D2(cyclinD2)、细胞周期蛋白依赖性激酶4(cyclin-de-pendentkinase4,CDK4)的表达,探讨它们与p27kip1蛋白表达、与临床病理指标的关系及其预后意义。