Objective To investigate the expression level of Shp-2 tyrosine phosphatase in chronic myeloid leukemia (CML) and its relationship with the unlimited growth and apoptosis resistance of p210 bcr/abl-induced malignant cells.

• 目的研究Src癌基因同源的酪氨酸蛋白磷酸酶2(Shp2)在慢性粒细胞白血病(CML)细胞中的表达,及其在p210bcr/abl诱导的白血病细胞恶性增殖和凋亡抵抗中的作用。