Objective To investigate the effect of angiotensin II receptor blocker(ARB)-valsartan and ACEI-benazeprilat on proliferation and hypertrophy induced by Ang II and PDGF in SHR mesangial cells.

• 目的观察ARB -valsartan及ACEI -benazeprilat能否抑制由AngII、PDGF引起的SHR肾小球系膜细胞的增殖与肥大。