Objective To investigate the effect of Bcl-2 ASODN on VP-16 induced growth inhibition and apoptosis in human bile duct carcinoma cell line QBC939. Methods Human cholangiocarcinoma cell line QBC939 was conventionally cultured.

• 目的探讨bcl-2反义寡核苷酸(ASODN)对VP-16抑制人胆管癌QBC939细胞生长和诱导细胞凋亡的影响。 方法合成特异性靶向Bcl-2ASODN,并将其转染QBC939细胞;