Objective To induce vancomycin-resistantant S aureus in vitro and to observe the changes of coagulase gene sequences of S. aureus and its relationship with vancomycin resistance.

• 摘要目的研究万古霉素敏感金黄色葡萄球菌经过体外诱导变成万古霉素中介耐药的金黄色葡萄球菌后凝固酶基因序列有无改变。