Objective To determine the expression of Rac1 in cultured human retinal pigment epithelial (RPE) cells under hypoxia,and to discuss the possible effect of Rac1 on the formation of choroidal neovascularization.

• 目的观察Rac1在缺氧条件下培养的视网膜色素上皮(retinal pigment epitheli-um,RPE)细胞的表达,以探讨其在脉络膜新生血管形成中可能的作用。