Objective To determine the ETO interaction domain of nuclear receptor co repressor (N CoR) for abolishing the biological function of AML1 ETO.

• 目的 为消除急性髓系白血病标志基因AML1/ETO的活性 ,确定核受体辅助抑制因子(nuclearreceptorco repressor,N CoR)与ETO基因相互作用的活性部位。