Objective To compare the curative effects of sodium hyaluronate(SH) or hyaluronidase(HD) to treat the patients with advanced scleroderma circumscriptum(ASC).

• 目的观察局部注射透明质酸钠(SH)或透明质酸酶(HD)治疗晚期限局性硬皮病(ASC)的临床效果,并进行比较分析。