Objective : To study lung injury of cardiac value replacement during cardiopulmonary bypass (CPB) and the protective effect and mechanism of Liposomal delivery of prostaglandin E1(Lipo-PGE1).

• 目的:探讨心脏瓣膜置换术中体外循环(CPB)导致的肺损伤以及静脉应用凯时注射液(前列地尔,Lipo-PGE_1)的肺保护作用及可能析机制。