OPG can reduce the number of mature osteoclast and depress the bone injury effect of osteoclast. Therefore, OPG could be a promised drug for patients suffered from hormonal induced osteonecrosis.

• 骨保护蛋白可以有效减少成熟破骨细胞数目并抑制其功能，在应用于激素性骨坏死的治疗中具有重要的价值。