OBJECTIVE: To prepare theophylline sustained-release tablets, examine the high polymer sustained-release materials and the hardness of the tablets effect on the releasing degree.

• 目的:制备茶碱缓释片剂,考察高分子缓释材料及片剂硬度对其释放度的影响。方法:调节乙基纤维素与羟丙甲纤维素的配比,制备不同的缓释片剂;