OBJECTIVE The present study was conducted to evaluate the effects of bifendate(dimethyl diphenyl bicarboxylate,DDB) on the pharmacokinetics of cyclosporine A(CsA) in Beagle dogs.

• 目的:考察联苯双酯(DDB)与环孢素A(CsA)在比格犬(beagle dog)体内合用后联苯双酯对CsA动力学过程的影响。