Non-paramet-ric linkage analyses:single-point analyses revealed that two adjacent loci on chromosome4q D4S413and D4S1597had evidence of linkage,with NPL-scores of2.04and2.23,and P values of0.021and0.014re-spectively.

• 非参数连锁分析:两点连锁分析揭示D4S413和D4S1597的NPL值分别为2.；04和2