No amplification products was observed in noneuronal wild COS 7 cells, but we can detect the expression of APP gene in COS 7 cell transfected with human APP gene, neuron like wild PC12 cells and human neuroblastoma SH SY5Y cells.

• 利用专门设计的引物不能检测野生型COS?7细胞中APP基因的表达，但可以检测转染人APP基因的非神经元类COS?7细胞，类神经元的野生型PC12及人神经母细胞瘤细胞SH?SY5Y细胞中APP基因的表达。