Nitropyridine-N-oxide was synthesized with pyridine as original reactant through N-oxidation and nitration reactions, by using water as medium, tungstic acid and sulfuric acid as catalysts.

• 在N-氧化反应中,因用水作为反应介质,钨酸和硫酸为催化剂,不仅降低了反应成本,减少了环境污染,而且N-氧化吡啶的产率较高为96。