Nimodipine liposomes could effectively protect the brain against damage, and were comparable to that after ip nimodipine injection but significantly better than that after ig administration.

• 结果表明,对小鼠抗脑缺氧、抗急性脑缺血及抗急性脑栓塞形成等均有显著的保护作用,其药效与腹腔注射尼莫地平溶液接近,显著优于灌胃给药。