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- NR2B protcin NR2B蛋白
- NR2B preiously has been implicated in the early stages of learning. 早先NR2B就被认为与学习的早期阶段有关。
- AbstractObjective:To explore the exPression of human c-kit recePtor protCin(c-kit R, CDl l7) in acute leukemia (AL). [目的]本研究主要探讨c-kit受体(c-kit R,CD117)在急性白血病(AL)中的表达及其临床意义。
- NR2B subtype selective NMDA receptor antagonists have received considerable attentions in recent years. 选择性N-甲基-D-天门冬氨酸受体NR2B亚型阻滞剂近年来受到了越来越多的关注。
- Objective:This study is to investigate the charateristics of the calcined bone as a carrer of bone morihogenetic protcin(BMP). 目的:将煅烧骨与骨形成蛋白复合,形成仿生骨植入动物体内以证明其为理想的载体。
- Drugs targeting forebrain NMDA NR2B receptors may serve as a new class of medicine to control persistent pain in humans. NMDA NR2B受体抑制剂在未来可能被用来控制人类的慢性痛.
- Currently, most of the NR2B antagonists known are structurally related to ifenprodil, and some belongs to the types of amides, amidines and aminoquinolines. 目前,已报道的NR2B亚型阻滞剂的结构类型绝大多数仍为艾芬地尔发展而来的哌啶衍生物,另外还有酰胺、脒、氨基喹啉等结构类型;
- With advances in understanding the structure of NMDA receptor, NR2B antagonist is expected to be a more effective candidate with little side effect to treat these diseases. 而NMDA受体NR2B亚单位分布相对集中,选择性NR2B拮抗剂有望成为更安全、有效、副作用低的一类新型药物。
- Shield or inhibition of ER retention motif within C1 cassette of NR1-1a subunit by NR2B subunit when assembling is not dependent on any particular region in NR2B C-terminus. NR2 B与 NR1- 1a装配时 ,NR2 B对 NR1- 1a C1盒中内质网滞留基序的遮蔽和阻滞作用 ,并不依赖于 NR2 B C末端某一特定的区域 ,相反可能仅要求有一定长度的 NR2 B C末端。
- The NR2B antagonists have shown the potential in neuronal protection and prophylaxis of hyperalgesia, drug-dependence and Parkinson's diseases in rodent models. NR2B亚型阻滞剂在神经元保护、镇痛、抗药物依赖、抗帕金森病等方面表现了潜力。
- Conclusion: FGR young rats had descended learning and memory abilities, the expression of NR2B and GluR1 subunit in CA1、CA3 region in their hippocampus is descended. 结论: FGR子鼠的学习记忆能力下降,其海马CA1、CA3区NR2B及GluR1表达下降;
- Divides the anticancer treatment effect which according to the NR2B Asia the sub-group decisive strength possibly produces, I have designed the parent compound. 根据NR2B亚分子组的决定性力量一节可能产生的抗癌效果,我设计了母体化合物。
- Result: ZBPY decoction serum pretreatment can down regulate the SNK mRNA induced by Glu, At the same time the mRNA expression of SPAR and PSD-95 were up-regulated and NR1, NR2A, NR2B were down-regulated. 对PSD-95 mRNA表达具有显著上调作用; 对NR1、NR2A、NR2B mRNA表达均有不同程度下调。
- p38 mnogen activated protcin kinase p38丝裂原活化蛋白激酶
- Keywords NMDA receptor;NR2B antagonists;ifenprodil;drug-dependence; NMDA受体;NR2B亚型阻滞剂;艾芬地尔;药物依赖;
- Keywords Premedication;Ketamine;Midazolam;NR2B;Hippocampus;rats; 麻醉前用药;氯胺酮;咪达唑仑;NR2B;海马;大鼠;
- Keywords Pain;N-methyl-D-aspartate receptor;NR2B subunits; 疼痛;N-甲基-D-天冬氨酸;受体;亚基;
- EFFECT OF INTRATHECAL KETAMINE ON THE EXPRESSION OF NR2B mRNA IN THE SPINAL CORD OF CCI RATS 氯胺酮鞘内注射对慢性坐骨神经损伤大鼠脊髓NMDA-2B mRNA表达的影响
- Studies on Molecular Mechanism of Learning and Memory Enhancement in NR2B Transgenic Mice NR2B转基因小鼠学习记忆能力增强的分子机理研究